Juha Nickels, Md. PhD. 
Publications

1. Nickels, J., Laasonen, E.: Heterotopia pancreatis. Duodecim 86: 133—1/40,1970.

2. Nickels, J., Elfving, G.: Sappirakon hyvänlaatuiset tuumorimaiset muodostumat. Duodecim 86: 730-735, 1970.

3. Nickels, J., Laasonen, E.: Review. Pancreatic heterotopia. Scand. J. Gastroenterol.5: 639—640, 1970.

4. Nickels, J.: Localisation of a microelectrode tip in muscle cell. A light and electron microscopic study. Acta physiol. Scand. 80: 360—369, 1970.

5. Nickels, J.: Correlation between the rise time of miniature end-plate potential and the distance of the recording microelectrode from the myoneural junction. Acta physiol. scand. 80: 370-377, 1970.

6. Nickels, J.: Hermolihasliitoksen patofysiologiaa. Duodecim 86: 1427—1434, 1970.

7. Nickels, J.: Plastic tissue embeddings as a demonstrating material in pathology. Brit. J. Med. Educ. 5: 246—247, 1971.

8. Nickels, J., Franssila, K., Hjelt, L.: Tymooma. Duodecim 87: 1192-1202, 1971.

9. Nickels, J.: A method for localisation of the muscle cell and the motor end—plate after in vivo registration with a microelectrode. Pflug. Arch. 330: 45-50, 1971.

10. Nickels, J., Franssila, K.: Seminoma of the anterior mediastinum. A case report with 10 year follow-up. Acta path. microbiol. scand. Section A. 80: 260—262, 1972.

11. Nickels, J., Friman, C.—E.: Chemodectoma of the lover mediastinum. Report of a case. Annales Chirurg. Gynaec. Fenn. 60: 124-127, 1972.

12. Nickels, J., Franssila, K., Hjelt, L.: Thymoma and Hodgkin’s disease of the thymus. Acta path. microbiol. scand. Sect. A 81: 1—5, 1973.
Also in: Acton, R.T.: Hodgkin’s disease II: Pathological considerations. MSS Infornation Corporation, New York, N.Y. p. 21—25, 1974.

13. Nickels, J.: Studies on microelectrode tip localization in muscle cell. Thesis, Helsinki 1973.

14. Nickels, J.: Fibre optics in the illumination of epoxy resin embedded cells. Microsc. Acta 76: Li8—50, 1974.

15. Nickels, J.: Peptic ulcer in hiatus hernia penetrating the heart. Brit. J. Dis. Chest 68: 273—278, 1974.

16. Nickels, J.: An ultramicrotome illuminator for epoxy resin embedded single cell specinen. Stain Technol. 50: 359—360, 1975.

17. Nickels, J., Franssila, K.: Thymoma metastasizing to extrathoracic sites. A case report. Acta pathol. microbiol. scand. Sect. A 84: 331—334, 1976.

18. Nickels, J.: Elektronimikroskopia kasvainten erotusdiagnostiikassa. Duodecim
92: 1292—1299, 1976.

19. Myllärniemi, H., Nickels, J.: Observations by scanning electron microscopy of normal and pathological human gall bladder epithelium. Acta pathol. microbiol. scand. Sect. A 85: 42—L48, 1977.

20. Mäkinen, J., Nickels, J.: Kudos— ja solupikanäytteet käytännön työssä. Suomen Lääkärilehti 32: 1691—1692, 1977.

21. Mäkinen, J., Nickels, J.  Halttunen, P. E.A.: Amyloid tumour of the lung. Report of a case and a short review of the literature. Acta pathol. microbiol. scand. Sect. A 85: 907—910, 1977.
Also in: Rheumatism Review, American Rheumatism Association, vol. 24.

22. Sipponen, P., Salaspuro, M., Nickels, J., Pikkarainen, P.: Orseiinilla värjäytyvät kasautumat maksasoluissa. Duodecim 94: 97—103, 1978.

23. Nickels, J., Risberg, B., Melander, S.: Trophoblastic pseudotumour of the uterus. Acta path. microbiol. scand. Sect. A 86: 14—16, 1978.

24. Collan, Y., Nickels, J., Kalima, T.V.: Lymphatics of the gallbladder mucosa in pigs. An electron microscope study. Lymphology 30-33, 1979.

25. Kalima, T.V., Nickels, J., Kivilaakso, E., Collan, Y.: Cholecystitis induced by lymphatic obstruction. Lymphology 154—158, 1979.

26. Koivuniemi, A., Nickels, J.: Synovial sarcoma diagnosed by fine-needle aspiration biopsy. A case report. Acta Cytol. 22: 515—518, 1978.

27. Nickels, J., Koivuniemi, A.: Cytology of malignant hemangiopericytoma. Acta Cytol. 23: 119—125, 1979.

28. Nickels, J., Koivuniemi, A., Heiskanen, 0.: Granulocytic sarcoma (chloroma) of the cerebellum and meninges. Acta Neurochirurg. 46: 297—301, 1979.

29. Tötterman, S., Ahovuo, J., Möller, C., Nickels, J.: Divertikelbildung am Afterkanal. Fortschr. Röntgenstr. 131: 223—224, 1979.

30. Salmi, J., Nickels, J.: Kliinispatologinen kokousselostus LVI. Duodecim 95: 499—507, 1979.

31. Mäkinen, J., Nickels, J.: Paraganglion cells mimicking metastatic clear cell carcinoma. Histopathology 3: 459—465, 1979.

32. Nickels, J., Kalima, T. V.: Leiomyosarcoma of the inferior vena cava. Vasa 8: 333-336, 1979.

33. Myllärniemi, H., Nickels, J.: Scanning electron microscopy of Crohn’s disease and ulcerative colitis of the colon. Virchows Arch. A Path. Anat. and Histol. 385: 343-350, 1980.

34. Vartio, T., Nickels, J., Höckerstedt, K., Scheinin, T.M.: Rhabdomyosarcoma of the oesophagus. Virchows Archiv A. Path. Anat. and Histol. 386:357—361, 1980.

35. Möller, C., Nickels, J., Sundell, B.: Implantation growth of adenocarcinoma after Kraske operation for rectal tubular adenoma. Virchows Arch. A Path. Anat. and Histol. 387: 235—239, 1980.

36. Nickels, J., Tahkokalllo, 0., Tukiainen, P.: Värekarvojen liikkumattomuus.
Duodecim 96: 857—862, 1980.

37. Risberg, B., Nickels, J., Wågermark, J.: Familial clustering of malignant mesothelioma. Cancer 45: 2422—2427, 1980.

38. Lehtonen, T., Mäkinen, J., Nickels, J., Permi, J.: Leydig cell tumor with gynecomastia. Report of a case with electron microscopy. Eur.Urol.6:364-367, 1980.

39. Harjula, A., Nickels, J., Mattila, S.: Histological study of glutaraldehyde—processed vascular grafts of biological origin. Annales chirurg. Cynaec. 69: 256-262, 1980.

40. Harjula, A., Myllärniemi, H., Nickels, J., Mattila, S.: Morphological study of flow surface of glutaraldehyde pre—treated vascular substitutes. Annales Chirurg.Gynaec. 69: 144—150,1980.

41. Tötterman, S., Lindfors, 0., Nickels, J.: A Schwannoma of the lesser omentum. Fortschr. Rontgenstr. 132: 585-586, 1980.

42. Vainio, H., Nickels, J., Heinonen, T.: Dose—related hepatotoxicity of 1,1,2—trichloro—1,2, 2—trifluoroethane in shortterm intermittent inhalation exposure in rats. Toxicology 18: 17—25, 1980.

43. Nickels, J., Vasama, M.: Oikeuslääketieteellinen ruumiinavaus ammattikuolemissa. Suomen Lääkärilehti 36: 1369-1370, 1981.

44. Harjula, A., Mattila, S., Härkönen, M., Myllärniemi, H., Nickels, J.: Danger of crystalloid cardioplegic solution. Proceedings of European Society for artificial organs. 8: 265—269, 1981.

45. Zitting, A., Savolainen, H., Nickels, J.: Acute effects of 2—nitropropane on rat liver and brain. Toxicology Letters 9: 237—246, 1981.

46. Santavirta, S., Ahonen, J., Nickels, J., Tötterman, S., Liewendahl, K.: Focal nodular hyperplasia of the liver. Acta Chir. Scand. 147: 73—77, 1981.

47. Vainio, H., Nickels, J., Linnainmaa, K.: Phenoxy acid herbicides cause peroxisome proliferation in Chinese hamsters. Scand. j. work environ, health. 8: 70-73, 1982.

48. Heinonen, T., Vainio, H., Nickels, J.: Effects of vinyltoluene alone and after pretreatment with polychlorinated biphenyls on hepatocellular morphology and enzyne activities in liver and kidneys in rats. Toxicology 22: 297—310, 1982.

49. Zitting, A., Savolainen, H., Nickels, J.: Biochemical and toxicological effects of single and repeated exposures to polyacetal thermodegradation products. Environ. Res. 29: 287—296, 1982.

50. Heinonen, T., Nickels, J., Vainio, H.: Subacute toxicity of vinyltoluene vapor: effects on the hepatic and renal drug biotransformation and the urinary excretion of thioether. Acta Pharmacol. Toxicol. 51: 69—75, 1982.

51. Huuskonen, M., Tossavainen, A., Koskinen, H., Zitting , A., Korhonen, 0., Nickels, J., Korhonen, K., Vaaranen, V.: Wollastonite exposure and lung fibrosis. Environ. Res. 30: 291-304, 1983.

52. Zitting, A., Nickels, J., Savolainen, H.: Comparison of acute toxic effects of intraperitoneally injected nitromethane and nitroethane in rats. Toxicol. Letters 13: 189-194, 1982.

53. Zitting, A., Szumanska, G., Nickels, J., Savolainen, H.: Acute toxic effects of trinitrotoluene on rat brain, liver and kidney: role of radical production. Arch. Toxicol. 51: 53-64, 1982.

54. Nickels, J., van Assendelft, A., Tukiainen, P.: Diffuse pulmonary injury associated with gold treatment. Acta path. microbiol. immunol. scand. Sect. A. 91: 265—267, 1983.

55. Harjula, A., Mattila, S., Mattila, I., Härkönen, M., Myllärniemi, H., Nickels, J., Merikallio, E.: Coronary endothelial damage after crystalloid cardioplegia. J. Cardiovasc. Surg. 25: 147—152, 1984.

56. Juntunen, J., Matikainen, E., Nickels, J., Ylikahri, R., Sarviharju, M.: Alcoholic neuropathy and hepatopathy in mice. Acta path. microbiol. immunol. scand. Sect. A. 91: 137—144, 1983.

57. Huuskonen, M., Järvisalo, J., Koskinen, H., Nickels, J., Räsänen, J., Asp, S.: Preliminary results from a cohort of workers exposed to wollastonite in a Finnish limestone quarry. Scand. j. work environ, health 9: 169—175, 1983.

58. Vainio, H., Linnainmaa, K., Kähönen, M., Nickels, J., Hietanen, E., Marniemi, J., Peltonen,P.: Hypolipidemia and peroxisome proliferation induced by phenoxyacetic acid herbicides in rats. Biochem. Pharmacol. 32: 2775-2779, 1983.

59. Telaranta, T., Solonen, K., Tallroth, K., Nickels, J.: Bone cysts containing silicone particles in bones adjacent to a carpal silastic implant. Skelatal radiol. 10: 247—249, 1983.	

60. Huuskonen, M., Järvisalo, J., Koskinen, H., Nickels, J. Pasanen, P., Tossavainen, A.: Kuitumineraalien aiheuttamat sairaudet. Duodecim 100: 197—205, 1984.

61. Keto, P., Suoranta, H., Myllärnieni, H., Nickels, J.: Areae gastricae in gastritis: lack of correlation between size and histology. Amer. J. Roentgenol. 141: 693-696, 1983.

62. Tenhunen, R., Zitting, A., Nickels, J., Savolainen, H.: Trinitrotoluene—induced effects on rat heme metabolisn. Experim. mol. pathol. 40: 362—366, 1984.

63. Tukiainen, P., Nickels, J., Taskinen, E., Nyberg, M.: Pulmonary granulomatous reaction: talc pneumoconiosis or chronic sarcoidosis? Brit. J. Industr. Med. 41: 84-87, 1984.

64. Vainiotalo, S., Zitting, A., Jacobsson, S., Nickels, J., Koskinen, H., Savolainen, H.: Toxicity of polymethylmetacrylate thermodegradation products. Arch. Toxicol. 55: 137—142,	1984.

65. Koskinen, H., Huuskonen, M., Järvisalo, J., Nickels, J., Pasanen, J., Tossavainen, A.: Kuitumineraalien aiheuttamat hengitystiesairaudet. Tuberkuloosi ja keuhkosairaudet 13: 82-86, 1984.

66. Harjula, A., Mattila, S., Myllärniemi, H., Nickels, J.: Glutaraldehyde-processed human veins as small vessel substitutes. Vasa 14: 16—20, 1985.

67. Elovaara, H., Engström, K., Nickels, J., Aitio, A., Vainio, H.: Biochemical and morphologic effects of long—term inhalation exposure of rats to ethylbenzene. Xenobiotica 15: 299—300, 1985.

68. Anttila, S., Sutinen, S., Kalliomäki, P—L., Nickels, J., Grekula, A., Sivonen, S.: Structure and composition of inhaled welding fumes in rat lung. In: Stern, R.M. et al.: Health hazards and biological effects of welding fumes and gases. Excerpta Medica, Amsterdam, New York, Oxford p. 353-356, 1986.

69. Partanen, T., Kauppinen, T., Nuutinen, M., Nickels, J., Hernberg, S., Hakulinen, T., Pukkala, E., Savonen, E.: Formaldehyde exposure and respiratory and related cancers. A case—referent study among Finnish woodworkers. Scand J Work Environ Health 11: 409—415, 1985.

70. Antti—Poika, M., Nordman, H., Nickels, J., Keskinen, H., Viljanen, A.: Lung disease after exposure to polyvinyl chloride dust. Thorax 41: 566—567, 1986.

71. Huuskonen, M. S., Tossavainen, A., Koskinen, H., Zitting, A., Korhonen, 0., Nickels, J., Korhonen, K., Vaaranen, V.: Respiratory morbidity of quarry workers exposed to wollastonite. In: Gee, J.B. et al: Occupational Lung Disease, Raven Press, New York p. 245, 1984.

72. Nickels, J.: Effects of organic solvents on liver cell morphology. In: Riihimäki , V. et al. Safety and Health Aspects of organic solvents, Alan R. Liss, Inc. New York,p.115—119, 1986.

73. Zitting, A., Savolainen, H., Nickels, J.: Intracellular production of free radicals: trinitrotoluene. In: Early diagnosis of the effects of toxic substances on the organism. Editors: Kahn, H., Hernberg, S. p. 67—70, 1984.

74. Vainiotalo, S., Verkkala, E., Savolainen, H., Nickels, J., Zitting, A.: Acute biological effects of commercial cresyl diphenyl phosphate in rats. Toxicology 44: 31—44, 1987.

75. Elovaara, E., Zitting, A., Nickels, J., Aitio, A.: m-Xylene inhalation destroys cytochrome P-450 in rat lung at low exposure. Arch. Toxicol. 61: 21—26, 1987.

76. Lindell, 0., Mäkinen, J., Nickels, J., Lehtonen, T.: Mucosal morphology of ileal conduits with particular reference to urinary infections. Eur. Urol. 12: 201-206,1986.

77. Tuomi, T., Tossavainen, A., Nickels, J., Stjernvall, T., Segerberg—Konttinen, N., Möttönen, M. Pölyn kertyminen keuhkokudokseen. Työsuojelurahaston tutkimusraportti, 1986.

78. Kauppinen, T., Partanen, T., Nurminen, M., Nickels, J., Hernberg, S., Hakulinen, T., Pukkala,E., Savonen, E.: Respiratory cancers and chemical exposures in the wood industry: A nested case—control study. Br. J. Ind. Med. 43: 84-90, 1986.

79. Partanen, T., Kauppinen, T., Hemberg, S., Nickels, J., Luukkonen, R., Hakulinen, T., Pukkala, E.: Formaldehyde exposure and respiratory cancer among woodworkers - an update. Scand. J. Work. Environ. Health.: 16: 394 - 400, 1990.

80. Brander, A., Viikinkoski, P., Nickels, J., Kivisaari, L.: Thyroid gland: US screening in middle-aged women with no previous thyroid disease. Radiology 173: 507-510, 1989.

81. Brander, A., Viikinkoski, P., Nickels, J., Kivisaari, L.: Thyroid gland: US Screening in a random adult population. Radiology 181: 683-687, 1991.

82. Kauppinen, T., Partanen, T., Hemberg, S., Nickels, J., Luukkonen, R., Hakulinen, T., Pukkala, E.: Chemical exposures and respiratory cancer among Finnish woodworkers. Br. J. Ind. Med. 50: 143 - 148, 1993.

83. Nickels, J.: BAL-tulkinta PC:lta. Suomen Lääkärilehti. 53: 218, 1998.

84. Nickels, J.: Valkosolujen erittely PC:n avulla. Suomen Lääkärilehti 54: 849 -851, 1999.

85. Brander, A., Viikinkoski, P., Nickels, J., Kivisaari, L.: Importance of thyroid abnormalities detected at US Screening: a 5-year follow-up. Radiology 215: 801-806, 2000.

86. Nickels, J.: BAL2000 tietokoneohjelma. Suomen Lääkärilehti 55: 2577-2578, 2000.

86: Nickels, J: Annapurna internetissä toimiva kevyt ajanvarausjärjestelmä Suomen Lääkärilehti 24: 2523-2525, 2004.

87. Nickels, J: Sumea logiikka lääkärin apulaisena. Nuori Lääkäri, 41: 28-31, 2004.

88. Nickels, J: Pikseliprostata – syövän tilavuuden laskentaohjelma. Erikoislääkäri 5: 211-214, 2005.

89. Nickels, J: PixelProstate - a simple software program for the measurement of prostate cancer volume. Histopathology 50: 519-521, 2007.

90: Nickels, J: Tuuti auttaa tuumorin tilavuuden määrityksessä. Erikoislääkäri 17: 206-209, 2007.


Software applications (download page http://www.nickels.fi):

1. Nickels, J.: BAL ver. 1.0 (DOS) An application for interpretation of bronchoalveolar lavage, 1995.

2. Nickels, J.: WinBAL ver. 2.0 (Win 3.1). An application for interpretation of bronchoalveolar lavage, 1997.

3. Nickels, J.: HemoDiff ver 1.0 (Win 3.1) An application for manual hematological calculations with PC, 1999.

4. Nickels, J.: BAL2000 ver.3.0 (Win95/98/NT) An application for interpretation of bronchoalveolar lavage, 2000.

5. Nickels, J.: Bal online - expert system on web 2001.

6. Nickels, J.: Annapurna - online appointment scheduling system ("IT Solution in Finnish Healthcare" Award winning 2004).

7. Nickels, J.: FuzzyFluid - cerebrospinal fluid expert system using fuzzy logic 2005.

8. Nickels, J.: PixelProstate - prostate cancer volume calculation ( with 3D rendering and T-classification), 2005.

9. Nickels, J.: Tuuti - tumour area and volume calculator, 2007.

10. Nickels, J.: PixArea – tumour area calculator, 2007.